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The abdominoperineal resection itself isassociated with an adverse outcome: the European experience based on a pooledanalysis of five European randomised clinical trials on rectal cancer. Theauthors found that teachers perceived the students with SLD to be less academ-ically competent and as having less social interaction than their peers withoutSLD. Sufficient dermal absorptionmay occur as to produce systemic effects. Tunica adventitia is well developed andcontains additional layers of smooth muscle fibers arranged in spiral,oblique, and longitudinal bundles

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Gonococcal infection was historically a relativelycommon etiology of septic arthritis in sexually active individuals; in the 1970s, Neisseriagonorrhoeae accounted for about two-thirds of septic arthritis and tenosynovitis cases inNorth America [25].

This is rare whenantimicrobial therapy was begun, in the firstplace, on sound clinical and/or bacteriologicalbasis.

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